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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T29431	4'-Azidothymidine 5'-triphosphate Adrt TP,Adrt-TP,AdrtTP
	4'-Azidothymidine 5'-triphosphate exerts selectively action on both reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta.
T4523	TP-3654	Pim	Chromatin/Epigenetic; JAK/STAT signaling
	TP3654是一种Pim 激酶抑制剂，对Pim-1和Pim-3的Ki 值分别为5和42 nM。
T34697	Splenopentin Thymopoietin III pentapeptide (32-36),Splenin pentapeptide (32-36),Arg-lys-glu-val-tyr
	Splenopentin (SP-5) is a synthetic immunomodulatory peptide that can reproduce the biological activity of TP and SP, respectively.
T36543	Prostaglandin B2 PGB2
	Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base. It has weak agonist activity on TP receptors and can increase pulmonary blood pressure in the rabbit at relatively high doses (5 ug/kg). [1]
T28494	R-82913 NSC 637653, 9-Cl-Tibo,R 82913,R82913. 9-Cmbib
	R-82913 is a RNA-directed DNA polymerase inhibitor. R 82913 reduce 5-HT2 receptor-mediated DOI-head-shakes in mice. R82913 inhibited the replication of thirteen different strains of HIV-1 in CEM cells with a median IC50 of 0.15 microM. R82913 was 20-fold
T36881	NHC-diphosphate triammonium
	NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2]. In an intracellular metabolism assay, HCV replicon cells are treated with 10 μM 3H-labeled NHC, and intracellular nucleotide levels are determined after 1, 2 and 8 hours incubations. NHC is rapidly convered into the mono...
T36490	AZT triphosphate TEA
	AZT triphosphate TFA (3'-Azido-3'-deoxythymidine-5'-triphosphate TFA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TFA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TFA also inhibits the DNA polymerase of HBV. AZT triphosphate TFA activates the mitochondria-mediated apoptosis pathway[1][2][3]. Treatment with 100 μM Zidovudine (AZT) for 48h disrupts the mitochondrial tubular network via accumulation of AZT triphosphate (AZT-TP) in ...
T35757	Beauvericin A
	Beauvericin A is a cyclodepsipeptide and derivative of beauvericin originally isolated fromB. bassianathat has diverse biological activities.1,2,3It is active againstM. tuberculosis(MIC = 25 μg/ml) andP. falciparum(IC50= 12 μg/ml).2Beauvericin A is toxic to brine shrimp (LD100= 32 μg/ml).3 1.Gupta, S., Montillor, C., and Hwang, Y.-S.Isolation of Novel Beauvericin Analogues from the Fungus Beauveria bassianaJ. Nat. Prod.58(5)733-738(1995) 2.Nilanonta, C., Isaka, M., Kittakoop, P., et al.Antimycob...

化合物

4'-Azidothymidine 5'-triphosphate

Cat.No: T29431

Synonym: Adrt TP,Adrt-TP,AdrtTP

Synonym: Thymopoietin III pentapeptide (32-36),Splenin pentapeptide (32-36),Arg-lys-glu-val-tyr

Synonym: NSC 637653, 9-Cl-Tibo,R 82913,R82913. 9-Cmbib

Target:

NHC-diphosphate triammonium

Cat. No.	Product Name	Target	Signaling Pathways
T2598	Thymopentin TP5,胸腺五肽	Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Thymopentin (TP5) 是主要由胸腺皮质和髓质上皮细胞分泌的生物特性肽。它能促使自人类胚胎干细胞产生 T 细胞群。它是有效免疫调节剂，具有很短的血浆半衰期(30 秒)。

天然产物

Thymopentin

Cat.No: T2598

Synonym: TP5,胸腺五肽

Target: Estrogen/progestogen Receptor, Endogenous Metabolite

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